Efficacy of orally administered sodium benzoate and sodium phenylbutyrate in dogs with congenital portosystemic shunts
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چکیده
منابع مشابه
A Patient with MSUD: Acute Management with Sodium Phenylacetate/Sodium Benzoate and Sodium Phenylbutyrate
In treatment of metabolic imbalances caused by maple syrup urine disease (MSUD), peritoneal dialysis, and hemofiltration, pharmacological treatments for elimination of toxic metabolites can be used in addition to basic dietary modifications. Therapy with sodium phenylacetate/benzoate or sodium phenylbutyrate (NaPB) in urea-cycle disorder cases has been associated with a reduction in branched-ch...
متن کاملPortosystemic shunts in dogs and cats: definition, epidemiology and clinical signs of congenital portosystemic shunts
Congenital portosystemic shunts (CPSS) are hepatic vascular anomalies which can affect any breed of dog or cat. Extrahepatic CPSS are most commonly observed in cats and small dogs, whereas intrahepatic CPSS are more likely to affect large breed dogs. A hereditary basis has been observed in some dog breeds. Affected animals are usually presented at young age with a variety of neurological, gastr...
متن کاملPortosystemic shunts in dogs and cats: laboratory diagnosis of congenital portosystemic shunts
The most frequent laboratory abnormalities in patients with congenital portosystemic shunts (CPSS) are microcytosis, hypoglycemia, hypoalbuminemia, hypoproteinemia, increased liver enzyme activities, decreased blood urea nitrogen (BUN) and urate crystalluria. The microcytosis is probably due to impaired iron transport. Hypoglycemia, hypoalbuminemia, hypoproteinemia and decreased BUN are partly ...
متن کاملImaging of Congenital Portosystemic Shunts
T he normal portal vascular system transports venous blood from the stomach, intestines, spleen, and pancreas to the hepatic sinusoids and ultimately the hepatic veins and caudal vena cava. Portosystemic shunting (PSS) occurs when abnormal vascular connections occur between the portal and systemic venous systems, bypassing the liver. This can be acquired secondary to portal hypertension arising...
متن کاملAssociation of breed with the diagnosis of congenital portosystemic shunts in dogs: 2,400 cases (1980-2002).
OBJECTIVE To determine the annual and overall proportion of diagnoses of congenital portosystemic shunts (CPSS) in dogs and identify breeds at increased risk for CPSS. DESIGN Retrospective study. ANIMALS 2,400 dogs with CPSS from veterinary teaching hospitals that reported to the Veterinary Medical Database (VMDB) from January 1, 1980 to February 28, 2002. PROCEDURE The proportion of diag...
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ژورنال
عنوان ژورنال: Journal of Veterinary Internal Medicine
سال: 2019
ISSN: 0891-6640,1939-1676
DOI: 10.1111/jvim.15477